Semantic Web

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Web 3.0 by Kate Ray

[Web 3.0 by Kate Ray]

Web 2.0, Web 3.0, Semantic Web, a short and simple introduction.

DC-THERA Directory, a Knowledge Management System for the support of the European Dendritic Cell Immunology Community

[dc-research.eu logo]Abstract. DC-THERA Directory is a web portal to support collaboration, communication and knowledge sharing within DC-THERA, a community focused on immunology. We show how we have faced the problem of repres- enting and managing highly heterogeneous and interconnected knowledge. One aspect of the application interface is the search and navigation through web ontologies. Another aspect is the dynamic representation of information entities having variable sets of properties. These results have been achieved by adopting a modelling approach that combines traditional object-oriented modelling with a triple-based knowledge representation. We discuss advantages of such an approach, especially for what concerns the possible future integration of other information sources.

(Late) notes from ISWC 2008

I've eventually found time to review the notes from the last International Semantic Web Conference conference and put them in a clean document. Yes, it's a bit late, but I like to put this here and maybe someone will still find it interesting.

If you like the longer reading, please see the slides below. If you're looking for just short impressions, I can summarize them as follows.

Networking with Dendritic Cells

I've recently gone to the hearth of Mediterranean, Athens, for the annual meeting of the DC-THERA network, an FP6 project. A number of people and organisations collaborate in the context of this project, under the hat of  dendritic cells research (DC). Even me, the amateurish biologist, can guess the importance of this kind of cells for the Immune system, and their consequent importance for the development of a number of vaccines and therapies.

Managing Microarray Knowledge with the Semantic Web

[MannOnto, relatedAssertions] Geeez! Eventually I have submitted the thesis and given the defense presentation! My PhD project is about representing the results coming from microarray data analysis. I represent concepts like: sets of differentially expressed genes, results from clustering algorithms, claims about the role of genes in a biological pathway. I use Semantic Web technologies and an OWL model (ontology) to provide a formal representation of such knowledge. All is focused on assertions (e.g.: "IL2 is expressed under LPS infection condition"), which may be supported by experimental evidence (e.g.: a data set) or other kinds of evaluations, including ranking and comments from the users. Moreover, users and their roles (e.g.: is an expert on Immunology) may be considedered, especially for ranking the assertions. I have also developed a demo, based on the Makna Semantic Wiki.





 

PhD project, yet another ontology

I have reviewed the OWL file once more. I have done it after analysis of study cases and considerations on making useful inference with OWL. Details are reported in the doc.

Gene Lists, Microarray Knowledge, Semantic Web

I've started this discussion on the semweb-lifesci mailing list. I was interested in how to handle gene lists in OWL (and other lists of gene expression related entities). The discussion has expanded toward: MAGE-OM in RDF format, microarrays and Semantic Web, Semantic web technologies...

Awkward identifiers

[Figures about TO gene]
Today I discovered that a gene named "to" exists. It's not difficult to imagine how much hope you have to find it in Google. That's interesting: it was mentioned on a discussion about the use of natural language identifiers in computer science modelling. But actually maybe it is a case that shows how the Semantic Web could be useful. And complement Google. Well, Google is still able to find meaning info by means of the extended name, "takeout". So, if you already know what "to" means you'll probaly look up it on a by-keyword search engine via "takeout" + something else (drosophila, gene). I wonder if marking something like "to" with something like "is the label for..." could actually improve searches. Uhm... probably relating "to or whatever" to other resources, such as publication or chromosome or who is studying this gene, to which disease or biological process is related to, etc. Uhm... Uhm... anyway I am impressed by this "to" thing...




PhD project, new version of the Ontology and Updates

I've reviewed the ontology, in favour of something rather simpler.

PhD, Progress report of Mar 2006

Now I am working on my project from the EBI. This is a progress report where I show the application of the Semantic Web to my stuff.